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The Kynurenine Pathway Is a Double-Edged Sword in Immune-Privileged Sites and in Cancer: Implications for Immunotherapy

The term “immune privilege” was originally coined to describe the suppression of inflammatory responses within organs protected by anatomic barriers, ie, the eyes, brain, placenta, and testes. However, cellular and metabolic processes, which orchestrate immune responses, also control inflammation wi...

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Detalhes bibliográficos
Publicado no:Int J Tryptophan Res
Main Authors: Routy, Jean-Pierre, Routy, Bertrand, Graziani, Gina M., Mehraj, Vikram
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063567/
https://ncbi.nlm.nih.gov/pubmed/27773992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/IJTR.S38355
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