Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth

BACKGROUND: Radiation therapy is the most commonly used postsurgical treatment for primary malignant brain tumors. Consequently, investigating the efficacy of chemotherapeutics combined with radiation for treating malignant brain tumors is of high clinical relevance. In this study, we examined the c...

詳細記述

保存先:
書誌詳細
出版年:Neuro Oncol
主要な著者: Hashizume, Rintaro, Zhang, Ali, Mueller, Sabine, Prados, Michael D., Lulla, Rishi R., Goldman, Stewart, Saratsis, Amanda M., Mazar, Andrew P., Stegh, Alexander H., Cheng, Shi-Yuan, Horbinski, Craig, Haas-Kogan, Daphne A., Sarkaria, Jann N., Waldman, Todd, James, C. David
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
Basic and Translational Investigation
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063519/
https://ncbi.nlm.nih.gov/pubmed/27370397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now106
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