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Induction of gut regulatory CD39(+) T cells by teriflunomide protects against EAE
OBJECTIVE: To determine whether as an orally delivered treatment, teriflunomide, an inhibitor of the mitochondrial enzyme dihydroorotate dehydrogenase approved to treat relapsing forms of multiple sclerosis, could affect gut-associated lymphoid tissue (GALT) immune responses functionally. METHODS: C...
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| Опубликовано в: : | Neurol Neuroimmunol Neuroinflamm |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Lippincott Williams & Wilkins
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5063394/ https://ncbi.nlm.nih.gov/pubmed/27766282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000291 |
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