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Prenatal deletion of DNA methyltransferase 1 in neural stem cells impairs neurogenesis and causes anxiety-like behavior in adulthood

Despite recent advances in our understanding of epigenetic regulation of central nervous system development, little is known regarding the effects of epigenetic dysregulation on neurogenesis and brain function in adulthood. In the present study, we show that prenatal deletion of DNA methyltransferas...

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Detalhes bibliográficos
Publicado no:Neurogenesis (Austin)
Main Authors: Noguchi, Hirofumi, Kimura, Ayaka, Murao, Naoya, Namihira, Masakazu, Nakashima, Kinichi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063063/
https://ncbi.nlm.nih.gov/pubmed/27844025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23262133.2016.1232679
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