Open PHACTS computational protocols for in silico target validation of cellular phenotypic screens: knowing the knowns

Phenotypic screening is in a renaissance phase and is expected by many academic and industry leaders to accelerate the discovery of new drugs for new biology. Given that phenotypic screening is per definition target agnostic, the emphasis of in silico and in vitro follow-up work is on the exploratio...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Digles, D., Zdrazil, B., Neefs, J.-M., Van Vlijmen, H., Herhaus, C., Caracoti, A., Brea, J., Roibás, B., Loza, M. I., Queralt-Rosinach, N., Furlong, L. I., Gaulton, A., Bartek, L., Senger, S., Chichester, C., Engkvist, O., Evelo, C. T., Franklin, N. I., Marren, D., Ecker, G. F., Jacoby, E.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063042/
https://ncbi.nlm.nih.gov/pubmed/27774140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00065g
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