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Using NMR and molecular dynamics to link structure and dynamics effects of the universal base 8-aza, 7-deaza, N8 linked adenosine analog
A truly universal nucleobase enables a host of novel applications such as simplified templates for PCR primers, randomized sequencing and DNA based devices. A universal base must pair indiscriminately to each of the canonical bases with little or preferably no destabilization of the overall duplex....
Sparad:
I publikationen: | Nucleic Acids Res |
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Huvudupphovsmän: | , , , , |
Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
Oxford University Press
2016
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5062995/ https://ncbi.nlm.nih.gov/pubmed/27566150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw736 |
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