Deferoxamine regulates neuroinflammation and iron homeostasis in a mouse model of postoperative cognitive dysfunction

BACKGROUND: Postoperative cognitive dysfunction (POCD) is a common complication after surgery, especially amongst elderly patients. Neuroinflammation and iron homeostasis are key hallmarks of several neurological disorders. In this study, we investigated the role of deferoxamine (DFO), a clinically...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Li, Yuping, Pan, Ke, Chen, Lin, Ning, Jiao-lin, Li, Xiaojun, Yang, Ting, Terrando, Niccolò, Gu, Jianteng, Tao, Guocai
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062909/
https://ncbi.nlm.nih.gov/pubmed/27733186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0740-2
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