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The Effects of Capillary Transit Time Heterogeneity (CTH) on the Cerebral Uptake of Glucose and Glucose Analogs: Application to FDG and Comparison to Oxygen Uptake

Glucose is the brain's principal source of ATP, but the extent to which cerebral glucose consumption (CMR(glc)) is coupled with its oxygen consumption (CMRO(2)) remains unclear. Measurements of the brain's oxygen-glucose index OGI = CMRO(2)/CMR(glc) suggest that its oxygen uptake largely s...

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Pubblicato in:Front Comput Neurosci
Autori principali: Angleys, Hugo, Jespersen, Sune N., Østergaard, Leif
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062759/
https://ncbi.nlm.nih.gov/pubmed/27790110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncom.2016.00103
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