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Bone marrow-derived and peritoneal macrophages have different inflammatory response to oxLDL and M1/M2 marker expression – implications for atherosclerosis research

Macrophages are heterogeneous and can polarize into specific subsets, e.g. pro-inflammatory M1-like and re-modelling M2-like macrophages. To determine if peritoneal macrophages (PEMs) or bone marrow derived macrophages (BMDMs) resembled aortic macrophages from ApoE−/− mice, their M1/M2 phenotype, in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bisgaard, Line S., Mogensen, Christina K., Rosendahl, Alexander, Cucak, Helena, Nielsen, Lars Bo, Rasmussen, Salka E., Pedersen, Tanja X.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062347/
https://ncbi.nlm.nih.gov/pubmed/27734926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35234
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