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Membrane Proteins Are Dramatically Less Conserved than Water-Soluble Proteins across the Tree of Life
Membrane proteins are crucial in transport, signaling, bioenergetics, catalysis, and as drug targets. Here, we show that membrane proteins have dramatically fewer detectable orthologs than water-soluble proteins, less than half in most species analyzed. This sparse distribution could reflect rapid d...
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| Publicado no: | Mol Biol Evol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5062322/ https://ncbi.nlm.nih.gov/pubmed/27501943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msw164 |
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