Identification of a novel serum biomarker for pancreatic cancer, C4b-binding protein α-chain (C4BPA) by quantitative proteomic analysis using tandem mass tags

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) remains a devastating disease due to the lack of specific early diagnostic markers. To improve the outcomes, proteomic approaches are being developed for the discovery of novel biomarkers of PDAC. METHODS: Using tandem mass tag labelling and LC-MS/...

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Udgivet i:Br J Cancer
Main Authors: Sogawa, Kazuyuki, Takano, Shigetsugu, Iida, Fumie, Satoh, Mamoru, Tsuchida, Sachio, Kawashima, Yusuke, Yoshitomi, Hideyuki, Sanda, Akihiro, Kodera, Yoshio, Takizawa, Hirotaka, Mikata, Rintaro, Ohtsuka, Masayuki, Shimizu, Hiroaki, Miyazaki, Masaru, Yokosuka, Osamu, Nomura, Fumio
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061912/
https://ncbi.nlm.nih.gov/pubmed/27657339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.295
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