Cholinergic Stimulation Prevents the Development of Autoimmune Diabetes: Evidence for the Modulation of Th17 Effector Cells via an IFNγ-Dependent Mechanism

Type I diabetes (T1D) results from T cell-mediated damage of pancreatic β-cells and loss of insulin production. The cholinergic anti-inflammatory pathway represents a physiological link connecting the central nervous and immune systems via vagus nerve, and functions to control the release of proinfl...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: George, Junu A., Bashir, Ghada, Qureshi, Mohammed M., Mohamed, Yassir A., Azzi, Jamil, al-Ramadi, Basel K., Fernández-Cabezudo, Maria J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061850/
https://ncbi.nlm.nih.gov/pubmed/27790217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00419
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