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Design and conduct of early phase drug studies in children: challenges and opportunities

It has historically been very difficult to conduct early phase drug studies in children for a number of reasons related to ethics, acceptability, rarity, standardization, end points, safety, dosing and feasibility. Over the past decade there have been a number of developments including novel clinica...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Rieder, Michael, Hawcutt, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061783/
https://ncbi.nlm.nih.gov/pubmed/27353241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13058
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