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Digitized Spiral Drawing: A Possible Biomarker for Early Parkinson’s Disease

INTRODUCTION: Pre-clinical markers of Parkinson’s Disease (PD) are needed, and to be relevant in pre-clinical disease, they should be quantifiably abnormal in early disease as well. Handwriting is impaired early in PD and can be evaluated using computerized analysis of drawn spirals, capturing kinem...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: San Luciano, Marta, Wang, Cuiling, Ortega, Roberto A., Yu, Qiping, Boschung, Sarah, Soto-Valencia, Jeannie, Bressman, Susan B., Lipton, Richard B., Pullman, Seth, Saunders-Pullman, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061372/
https://ncbi.nlm.nih.gov/pubmed/27732597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162799
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