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The essential role of spermidine in growth of Agrobacterium tumefaciens is determined by the 1,3-diaminopropane moiety

The ubiquitous polyamine spermidine is indispensable for eukaryotic growth and cell proliferation. A conserved vital function of spermidine across eukaryotes is conferred by its aminobutyl group that is transferred to a single lysine in translation factor eIF5A to form the essential hypusine post-tr...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Kim, Sok Ho, Wang, Yi, Khomutov, Maxim, Khomutov, Alexey, Fuqua, Clay, Michael, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061148/
https://ncbi.nlm.nih.gov/pubmed/26682642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00893
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