Proteomic profiling identifies PTK2/FAK as a driver of radioresistance in HPV-negative head and neck cancer

PURPOSE: Head and neck squamous cell carcinoma (HNSCC) is commonly treated with radiotherapy, and local failure after treatment remains the major cause of disease-related mortality. To date human papillomavirus (HPV) is the only known clinically validated, targetable biomarkers of response to radiat...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Skinner, Heath D., Giri, Uma, Yang, Liang P., Woo, Sang Hyeok, Story, Michael, Pickering, Curtis, Byers, Lauren, Williams, Michelle, El Naggar, Adel, Wang, Jing, Diao, Lixia, Shen, Li, Fan, You Hong, Molkentine, David, Beadle, Beth, Meyn, Raymond, Myers, Jeffrey, Heymach, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061056/
https://ncbi.nlm.nih.gov/pubmed/27036135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2785
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