Transcription-dependent and transcription-independent nucleosome disruption induced by dioxin.
In mouse hepatoma cells, both the regulatory and the transcribed regions of the cyp1a1 gene assume a nucleosomal configuration when the gene is silent; two nucleosomes occupy specific sites at the transcriptional promoter. Activation of transcription by 2,3,7,8-tetrachlorodibenzo-p-dioxin is accompa...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50605/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11622 |
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