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Retroviral vectors and transposons for stable gene therapy: advances, current challenges and perspectives

Gene therapy protocols require robust and long-term gene expression. For two decades, retrovirus family vectors have offered several attractive properties as stable gene-delivery vehicles. These vectors represent a technology with widespread use in basic biology and translational studies that requir...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Vargas, José Eduardo, Chicaybam, Leonardo, Stein, Renato Tetelbom, Tanuri, Amilcar, Delgado-Cañedo, Andrés, Bonamino, Martin H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059932/
https://ncbi.nlm.nih.gov/pubmed/27729044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1047-x
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