Capsaicin mediates caspases activation and induces apoptosis through P38 and JNK MAPK pathways in human renal carcinoma

BACKGROUND: Renal cell carcinoma (RCC) is one of the tumors most refractory to chemotherapy to date. Therefore, novel therapeutic agents are urgently needed for this disease. Capsaicin (CPS), a natural active ingredient of green and red peppers, and a ligand of transient receptor potential vanilloid...

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Publicat a:BMC Cancer
Autors principals: Liu, Tao, Wang, Gang, Tao, Huangheng, Yang, Zhonghua, Wang, Yongzhi, Meng, Zhe, Cao, Rui, Xiao, Yu, Wang, Xinghuan, Zhou, Jiajie
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059898/
https://ncbi.nlm.nih.gov/pubmed/27729033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2831-y
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