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Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure

Acute liver failure (ALF) is a life-threatening systemic disorder. Here we investigated the impact of circulating histones, recently identified inflammatory mediators, on systemic inflammation and liver injury in murine models and patients with ALF. We analyzed histone levels in blood samples from 6...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wen, Zongmei, Lei, Zhen, Yao, Lu, Jiang, Ping, Gu, Tao, Ren, Feng, Liu, Yan, Gou, Chunyan, Li, Xiuhui, Wen, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059889/
https://ncbi.nlm.nih.gov/pubmed/27685635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.303
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