Kinsenoside screening with a microfluidic chip attenuates gouty arthritis through inactivating NF-κB signaling in macrophages and protecting endothelial cells

Gouty arthritis is a rheumatic disease that is characterized by the deposition of monosodium urate (MSU) in synovial joints cause by the increased serum hyperuricemia. This study used a three-dimensional (3D) flowing microfluidic chip to screen the effective candidate against MSU-stimulated human um...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Han, Qiao, Bing, Wang, Di, Yin, Hua, Li, Shi-he, Li, Yu-hua, Zheng, Xiu-guo, Han, Yu-gang, Wang, Qi-ming, Fan, Shih-mo, Yang, Ting-ting, Tang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059859/
https://ncbi.nlm.nih.gov/pubmed/27584788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.255
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