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A plasma membrane microdomain compartmentalizes ephrin-generated cAMP signals to prune developing retinal axon arbors

The development of neuronal circuits is controlled by guidance molecules that are hypothesized to interact with the cholesterol-enriched domains of the plasma membrane termed lipid rafts. Whether such domains enable local intracellular signalling at the submicrometre scale in developing neurons and...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Averaimo, Stefania, Assali, Ahlem, Ros, Oriol, Couvet, Sandrine, Zagar, Yvrick, Genescu, Ioana, Rebsam, Alexandra, Nicol, Xavier
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059439/
https://ncbi.nlm.nih.gov/pubmed/27694812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12896
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