Phosphorylation state and DNA-binding activity of c-Jun depend on the intracellular concentration of binding sites.
The DNA-binding activity of c-Jun expressed in eukaryotic cells was found to be markedly enhanced if the intracellular concentration of binding sites for this transcription factor was increased by cotransfection of specific plasmid DNA. Dephosphorylation experiments, phosphate mapping studies, and m...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50592/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454848/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11562 |
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