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Calcium handling precedes cardiac differentiation to initiate the first heartbeat

The mammalian heartbeat is thought to begin just prior to the linear heart tube stage of development. How the initial contractions are established and the downstream consequences of the earliest contractile function on cardiac differentiation and morphogenesis have not been described. Using high-res...

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Tyser, Richard CV, Miranda, Antonio MA, Chen, Chiann-mun, Davidson, Sean M, Srinivas, Shankar, Riley, Paul R
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059139/
https://ncbi.nlm.nih.gov/pubmed/27725084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17113
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