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Myofiber-specific TEAD1 overexpression drives satellite cell hyperplasia and counters pathological effects of dystrophin deficiency

When unperturbed, somatic stem cells are poised to affect immediate tissue restoration upon trauma. Yet, little is known regarding the mechanistic basis controlling initial and homeostatic ‘scaling’ of stem cell pool sizes relative to their target tissues for effective regeneration. Here, we show th...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Southard, Sheryl, Kim, Ju-Ryoung, Low, SiewHui, Tsika, Richard W, Lepper, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059137/
https://ncbi.nlm.nih.gov/pubmed/27725085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15461
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