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Tat-responsive region RNA of human immunodeficiency virus type 1 stimulates protein synthesis in vivo and in vitro: relationship between structure and function.

The Tat-responsive region (TAR) sequence is present at the 5' end of human immunodeficiency virus 1 mRNAs and as a cytoplasmic form of 58-66 nucleotides. TAR RNA blocks the activation and autophosphorylation of the double-stranded RNA-activated protein kinase in vitro. We show here that TAR RNA also...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Gunnery, S, Green, S R, Mathews, M B
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1992
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50591/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1360669/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11557
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