xCT increases tuberculosis susceptibility by regulating antimicrobial function and inflammation

The physiological functions of macrophage, which plays a central role in the pathogenesis of tuberculosis, depend on its redox state. System xc-, a cystine-glutamate transporter, which consists of xCT and CD98, influences many ROS-dependent pathways by regulating the production of the antioxidant gl...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Cai, Yi, Yang, Qianting, Liao, Mingfeng, Wang, Hao, Zhang, Chi, Nambi, Subhalaxmi, Wang, Wenfei, Zhang, Mingxia, Wu, Junying, Deng, Guofang, Deng, Qunyi, Liu, Haiying, Zhou, Boping, Jin, Qi, Feng, Carl G, Sassetti, Christopher M, Wang, Fudi, Chen, Xinchun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058734/
https://ncbi.nlm.nih.gov/pubmed/27129162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9052
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi