Integrin signaling via FAK-Src controls cytokinetic abscission by decelerating PLK1 degradation and subsequent recruitment of CEP55 at the midbody

Adhesion to extracellular matrix is required for cell cycle progression through the G1 phase and for the completion of cytokinesis in normal adherent cells. Cancer cells acquire the ability to proliferate anchorage-independently, a characteristic feature of malignantly transformed cells. However, th...

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Sparad:
Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Kamranvar, Siamak A., Gupta, Deepesh Kumar, Huang, Ying, Gupta, Rajesh Kumar, Johansson, Staffan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058720/
https://ncbi.nlm.nih.gov/pubmed/27127172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9003
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