MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-κB and NLRP3 inflammasome activation

Mucosa-associated-lymphoid-tissue lymphoma-translocation gene 1 (MALT1), a paracaspase and essential regulator for nuclear factor kB (NF-κB) activation, plays an important role in innate and adaptive immunity. Suppression of MALT1 protease activity with small molecule inhibitors showed promising eff...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Wen, Guo, Wenjie, Hang, Nan, Yang, Yuanyuan, Wu, Xuefeng, Shen, Yan, Cao, Jingsong, Sun, Yang, Xu, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058699/
https://ncbi.nlm.nih.gov/pubmed/27105502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8867
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