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Plumbagin Suppresses the Invasion of HER2-Overexpressing Breast Cancer Cells through Inhibition of IKKα-Mediated NF-κB Activation

HER2-overexpressing breast cancers account for about 30% of breast cancer occurrences and have been correlated with increased tumor aggressiveness and invasiveness. The nuclear factor-κB (NF-κB) is overexpressed in a subset of HER2-positive breast cancers and its upregulation has been associated wit...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Kawiak, Anna, Domachowska, Anna
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058502/
https://ncbi.nlm.nih.gov/pubmed/27727280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164064
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