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Diminished skeletal muscle microRNA expression with aging is associated with attenuated muscle plasticity and inhibition of IGF-1 signaling

Older individuals have a reduced capacity to induce muscle hypertrophy with resistance exercise (RE), which may contribute to the age-induced loss of muscle mass and function, sarcopenia. We tested the novel hypothesis that dysregulation of microRNAs (miRNAs) may contribute to reduced muscle plastic...

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書目詳細資料
發表在:FASEB J
Main Authors: Rivas, Donato A., Lessard, Sarah J., Rice, Nicholas P., Lustgarten, Michael S., So, Kawai, Goodyear, Laurie J., Parnell, Laurence D., Fielding, Roger A.
格式: Artigo
語言:Inglês
出版: Federation of American Societies for Experimental Biology 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058318/
https://ncbi.nlm.nih.gov/pubmed/24928197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-254490
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