Poly(L-alanine) as a universal reference material for understanding protein energies and structures.

We present a proposition, the "poly(L-alanine) hypothesis," which asserts that the native backbone geometry for any polypeptide or protein of M residues has a closely mimicking, mechanically stable, image in poly(L-alanine) of the same number of residues. Using a molecular mechanics force field to r...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Head-Gordon, T, Stillinger, F H, Wright, M H, Gay, D M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50582/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454840/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11513
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