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Histone lysine methyltransferases as anti-cancer targets for drug discovery
Post-translational epigenetic modification of histones is controlled by a number of histone-modifying enzymes. Such modification regulates the accessibility of DNA and the subsequent expression or silencing of a gene. Human histone methyltransferases (HMTs)constitute a large family that includes his...
Gorde:
| Argitaratua izan da: | Acta Pharmacol Sin |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5057236/ https://ncbi.nlm.nih.gov/pubmed/27397541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.64 |
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