Role of IgM and Angiotensin II Type I Receptor Autoantibodies in Local Complement Activation in Placental Ischemia-induced Hypertension in the Rat

Preeclampsia is characterized by development of hypertension during pregnancy and reduced placental perfusion. Previous studies in a rat model of placental ischemia-induced hypertension demonstrated that inhibiting complement activation attenuated increased maternal blood pressure with C3a and C5a i...

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Detalhes bibliográficos
Publicado no:Mol Immunol
Main Authors: Regal, Jean F, Strehlke, Megan E, Peterson, Jenna M, Wing, Cameron R, Parker, Jordan E, Nieto, Noel Fernando, Bemis, Lynne T, Gilbert, Jeffrey S, Fleming, Sherry D
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056842/
https://ncbi.nlm.nih.gov/pubmed/27588825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2016.08.016
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