Photodynamic vaccination of hamsters with inducible suicidal mutants of Leishmania amazonensis elicits immunity against visceral leishmaniasis

Leishmania, naturally residing in the phagolysosomes of macrophages, is a suitable carrier for vaccine delivery. Genetic complementation of these trypanosomatid protozoa to partially rectify their defective heme-biosynthesis renders them inducible with δ-aminolevulinate to develop porphyria for sele...

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Veröffentlicht in:Eur J Immunol
Hauptverfasser: Kumari, Shraddha, Samant, Mukesh, Khare, Prashant, Misra, Pragya, Dutta, Sujoy, Kolli, Bala Krishna, Sharma, Sharad, Chang, Kwang Poo, Dube, Anuradha
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056643/
https://ncbi.nlm.nih.gov/pubmed/19053149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838389
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