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A PTEN inhibitor displays preclinical activity against hepatocarcinoma cells
Phosphatase and tensin homolog (PTEN) gene is considered a tumor suppressor gene. However, PTEN mutations rarely occur in hepatocellular carcinoma (HCC), whereas heterozygosity of PTEN, resulting in reduced PTEN expression, has been observed in 32–44% of HCC patients. In the present study, we invest...
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Gepubliceerd in: | Cell Cycle |
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Hoofdauteurs: | , , , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Taylor & Francis
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5056616/ https://ncbi.nlm.nih.gov/pubmed/26794644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1138183 |
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