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Dynamic actin cycling through mitochondrial subpopulations locally regulates the fission–fusion balance within mitochondrial networks

Mitochondria form interconnected networks that dynamically remodel in response to cellular needs. Using live-cell imaging, we investigate the role of the actin cytoskeleton in regulating mitochondrial fission and fusion. We identify cycling of actin filaments onto and off of subsets of cellular mito...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Moore, Andrew S., Wong, Yvette C., Simpson, Cory L., Holzbaur, Erika L. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056443/
https://ncbi.nlm.nih.gov/pubmed/27686185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12886
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