Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM

The β-barrel assembly machinery (BAM) is a ∼203 kDa complex of five proteins (BamA–E), which is essential for viability in E. coli. BAM promotes the folding and insertion of β-barrel proteins into the outer membrane via a poorly understood mechanism. Several current models suggest that BAM functions...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Iadanza, Matthew G., Higgins, Anna J., Schiffrin, Bob, Calabrese, Antonio N., Brockwell, David J., Ashcroft, Alison E., Radford, Sheena E., Ranson, Neil A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056442/
https://ncbi.nlm.nih.gov/pubmed/27686148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12865
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