Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue

Although protein ADP-ribosylation is involved in diverse biological processes, it has remained a challenge to identify ADP-ribose acceptor sites. Here, we present an experimental workflow for sensitive and unbiased analysis of endogenous ADP-ribosylation sites, capable of detecting more than 900 mod...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Martello, Rita, Leutert, Mario, Jungmichel, Stephanie, Bilan, Vera, Larsen, Sara C., Young, Clifford, Hottiger, Michael O., Nielsen, Michael L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056437/
https://ncbi.nlm.nih.gov/pubmed/27686526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12917
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