Enrichment of hydroxylated C24- and C26-acyl-chain sphingolipids mediates PIN2 apical sorting at trans-Golgi network subdomains

The post-Golgi compartment trans-Golgi Network (TGN) is a central hub divided into multiple subdomains hosting distinct trafficking pathways, including polar delivery to apical membrane. Lipids such as sphingolipids and sterols have been implicated in polar trafficking from the TGN but the underlyin...

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Udgivet i:Nat Commun
Main Authors: Wattelet-Boyer, Valérie, Brocard, Lysiane, Jonsson, Kristoffer, Esnay, Nicolas, Joubès, Jérôme, Domergue, Frédéric, Mongrand, Sébastien, Raikhel, Natasha, Bhalerao, Rishikesh P., Moreau, Patrick, Boutté, Yohann
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056404/
https://ncbi.nlm.nih.gov/pubmed/27681606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12788
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