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FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase

Dopaminergic (DA) neurons are involved in the integration of neuronal and hormonal signals to regulate food consumption and energy balance. Forkhead transcriptional factor O1 (FoxO1) in the hypothalamus plays a crucial role in mediation of leptin and insulin function. However, the homoeostatic role...

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Foilsithe in:Nat Commun
Main Authors: Doan, Khanh V., Kinyua, Ann W., Yang, Dong Joo, Ko, Chang Mann, Moh, Sang Hyun, Shong, Ko Eun, Kim, Hail, Park, Sang-Kyu, Kim, Dong-Hoon, Kim, Inki, Paik, Ji-Hye, DePinho, Ronald A., Yoon, Seul Gi, Kim, Il Yong, Seong, Je Kyung, Choi, Yun-Hee, Kim, Ki Woo
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056402/
https://ncbi.nlm.nih.gov/pubmed/27681312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12733
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