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Use of Bacteriophage to Target Bacterial Surface Structures Required for Virulence: A Systematic Search for Antibiotic Alternatives
Bacteriophage (phage) that infect pathogenic bacteria often attach to surface receptors that are coincidentally required for virulence. Receptor loss or modification through mutation renders mutants both attenuated and phage resistant. Such attenuated mutants frequently have no apparent laboratory g...
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Publicado no: | Curr Genet |
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Autor principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5056124/ https://ncbi.nlm.nih.gov/pubmed/27113766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-016-0603-5 |
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