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Use of Bacteriophage to Target Bacterial Surface Structures Required for Virulence: A Systematic Search for Antibiotic Alternatives

Bacteriophage (phage) that infect pathogenic bacteria often attach to surface receptors that are coincidentally required for virulence. Receptor loss or modification through mutation renders mutants both attenuated and phage resistant. Such attenuated mutants frequently have no apparent laboratory g...

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Detalhes bibliográficos
Publicado no:Curr Genet
Autor principal: Orndorff, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056124/
https://ncbi.nlm.nih.gov/pubmed/27113766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-016-0603-5
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