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Three-dimensional localization of T-cell receptors in relation to microvilli using a combination of superresolution microscopies

Leukocyte microvilli are flexible projections enriched with adhesion molecules. The role of these cellular projections in the ability of T cells to probe antigen-presenting cells has been elusive. In this study, we probe the spatial relation of microvilli and T-cell receptors (TCRs), the major molec...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Jung, Yunmin, Riven, Inbal, Feigelson, Sara W., Kartvelishvily, Elena, Tohya, Kazuo, Miyasaka, Masayuki, Alon, Ronen, Haran, Gilad
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056101/
https://ncbi.nlm.nih.gov/pubmed/27647916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605399113
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