Rhubarb extract partially improves mucosal integrity in chemotherapy-induced intestinal mucositis

AIM: To investigate the effects of orally gavaged aqueous rhubarb extract (RE) on 5-fluorouracil (5-FU)-induced intestinal mucositis in rats. METHODS: Female Dark Agouti rats (n = 8/group) were gavaged daily (1 mL) with water, high-dose RE (HDR; 200 mg/kg) or low-dose RE (LDR; 20mg/kg) for eight day...

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Bibliographic Details
Published in:World J Gastroenterol
Main Authors: Bajic, Juliana E, Eden, Georgina L, Lampton, Lorrinne S, Cheah, Ker Y, Lymn, Kerry A, Pei, Jinxin V, Yool, Andrea J, Howarth, Gordon S
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2016
Subjects:
Basic Study
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055863/
https://ncbi.nlm.nih.gov/pubmed/27729739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i37.8322
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