Discovery of immunodominant T-cell epitopes reveals penton protein as a second immunodominant target in human adenovirus infection

BACKGROUND: Human adenovirus (HAdV) infections remain a significant cause of morbidity and mortality after hematopoietic stem cell transplantation (HSCT). Efficient antiviral T-cell responses are necessary to clear infection, which is hampered by delayed immune reconstitution and medical immunosuppr...

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Foilsithe in:J Transl Med
Main Authors: Tischer, Sabine, Geyeregger, René, Kwoczek, Julian, Heim, Albert, Figueiredo, Constanca, Blasczyk, Rainer, Maecker-Kolhoff, Britta, Eiz-Vesper, Britta
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2016
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055684/
https://ncbi.nlm.nih.gov/pubmed/27717382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1042-2
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