Proinflammatory cytokines decrease the expression of genes critical for RPE function

PURPOSE: Proinflammatory cytokines interferon gamma (IFN-γ), tumor necrosis factor alpha (TNF-α), and interleukin-1 beta (IL-1β) secreted by infiltrating lymphocytes or macrophages may play a role in triggering RPE dysfunction associated with age-related macular degeneration (AMD). Binding of these...

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Udgivet i:Mol Vis
Main Authors: Kutty, R. Krishnan, Samuel, William, Boyce, Kaifa, Cherukuri, Aswini, Duncan, Todd, Jaworski, Cynthia, Nagineni, Chandrasekharam N., Redmond, T. Michael
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Vision 2016
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055142/
https://ncbi.nlm.nih.gov/pubmed/27733811
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