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The value of patient selection in demonstrating treatment effect in stroke recovery trials: lessons from the CHIMES study of MLC601 (NeuroAiD)

OBJECTIVE: The CHIMES Study compared MLC601 to placebo in patients with ischemic stroke of intermediate severity in the preceding 72 hours. We aimed to verify if patient selection based on two prognostic factors (ie, stroke severity and time to treatment) improves detection of a treatment effect wit...

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Detalhes bibliográficos
Publicado no:J Evid Based Med
Main Authors: Venketasubramanian, Narayanaswamy, Lee, Chun Fan, Wong, K. S. Lawrence, Chen, Christopher L. H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054909/
https://ncbi.nlm.nih.gov/pubmed/26291445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jebm.12170
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