Thymic depletion and peripheral activation of class I major histocompatibility complex-restricted T cells by soluble peptide in T-cell receptor transgenic mice.

Injection of mice transgenic for a class I major histocompatibility complex-restricted T-cell receptor with a soluble peptide antigen from influenza virus nucleoprotein results in clonal depletion of double-positive immature thymocytes in the thymus and activation of mature T cells in the periphery,...

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Main Authors: Mamalaki, C, Norton, T, Tanaka, Y, Townsend, A R, Chandler, P, Simpson, E, Kioussis, D
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC50546/
https://ncbi.nlm.nih.gov/pubmed/1360667
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