Laddar...

AML1/ETO accelerates cell migration and impairs cell-to-cell adhesion and homing of hematopoietic stem/progenitor cells

The AML1/ETO fusion protein found in acute myeloid leukemias functions as a transcriptional regulator by recruiting co-repressor complexes to its DNA binding site. In order to extend the understanding of its role in preleukemia, we expressed AML1/ETO in a murine immortalized pluripotent hematopoieti...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Saia, Marco, Termanini, Alberto, Rizzi, Nicoletta, Mazza, Massimiliano, Barbieri, Elisa, Valli, Debora, Ciana, Paolo, Gruszka, Alicja M., Alcalay, Myriam
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054523/
https://ncbi.nlm.nih.gov/pubmed/27713544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34957
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!