Preclinical Identification of Vaccine Induced Protective Correlates in Human Leukocyte Antigen Expressing Transgenic Mice Infected with Coccidioides posadasii

There is an emerging interest to develop human vaccines against medically-important fungal pathogens and a need for a preclinical animal model to assess vaccine efficacies and protective correlates. HLA-DR4 (DRB1*0401 allele) transgenic mice express a human major histocompatibility complex class II...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Hurtgen, Brady J., Castro-Lopez, Natalia, del Pilar Jiménez-Alzate, Maria, Cole, Garry T., Hung, Chiung-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053907/
https://ncbi.nlm.nih.gov/pubmed/27622300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.08.078
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